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“எண்ணிய முடிதல் வேண்டும்,

நல்லவே எண்ணல் வேண்டும்;

திண்ணிய நெஞ்சம் வேண்டும்,

தெளிந்தநல் லறிவு வேண்டும்;”

        - மகாகவி சி. சுப்பிரமணிய பாரதி

“Let my thoughts bloom into action;

Let me think only noble thoughts;

Let me have valiant heart;

Let me have a clear wisdom;"

         - Mahakavi C. Subramania Bharathiar

PROFILE

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

Research Area Image

Research Area

  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics
Course Teaching / Taught

Courses Teaching

  • Environmental Toxicology
  • Data Analytics and Research Methods
  • Environmental Biotechnology
  • Environmental Health
  • Industry 4.0
  • Environmental Impact Assessment

EDUCATION & CAREER

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

Education

Ph. D.
Subject : Biotechnology
Institution : Annamalai University          
Affiliated University : Annamalai University
Year of Award : 2014

M.Phil.,
Subject : Biotechnology
Institution : Annamalai University          
Affiliated University : Annamalai University
Year of Award : 2011

M.Sc.,
Subject : Biotechnology
Institution : Annamalai University          
Affiliated University : Annamalai University
Year of Award : 2009

 

Career

At Bharathiar University (Reverse Order)

Assistant Professor : **** to Till Date

Past Experience
Post-doctoral Fellow: April 2014 to Jan 2016 at Anna University – KBC RC
Young Scientist : Feb 2016 to Nov 2016 at Anna University – KBC RC

RESEARCH AREAS

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

PUBLICATIONS

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

2021

Accordion content 1.

2020-2010

1. Thalidomide and its analogs differentially target Fibroblast Growth Factor Receptors: Thalidomide suppresses FGFR gene expression while pomalidomide dampens FGFR2 activity
Name of the Authors : L Sundaresan, P Kumar, J Manivannan, S Chatterjee
Chemical Research in Toxicology 32 (4), 589-602 (2019).

2.A proteome-wide systems toxicological approach deciphers the interaction network of chemotherapeutic drugs in the cardiovascular milieu
Name of the Authors : S Giri, J Manivannan, B Srinivasan, S Chatterjee.
RSC Advances 8, 20211-20221(2018)

3.Transcriptomic analysis of thalidomide challenged chick embryo suggests possible link between impaired vasculogenesis and defective organogenesis
Name of the Authors :V Veeriah, P Kumar, L Sundaresan, Z Mafitha, J.Manivannan, S.Chattejee
Chemical Research in Toxicology 30 (10), 1883-1896 (2017).

4. A novel liquid chromatography/tandem mass spectrometry (LC–MS/MS) based bioanalytical method for quantification of ethyl esters of Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) and its application in pharmacokinetic study
Name of the Authors :S Viswanathan, PRP Verma, MGanesan, J Manivannan.
J Pharm Biomed Anal.141:250-261 (2017)

5.Oxidative environment causes molecular remodeling in embryonic heart-a metabolomic and lipidomic fingerprinting analysis
Name of the Authors :S Manickaraj, D Thirumalai, P Manjunath P, V Sekarbabu, Jeganathan M.
Life Science Archives 3 (2), 981-985(2017)

6.Environmental endocrine disrupting chemicals (EDCs) and its systems level toxicological mechanisms – an environmental health study
Name of the Authors :J Manivannan and S Usha
J Pharm Biomed Anal.141:250-261 (2017)

7.Disturbed flow mediated modulation of shear forces on endothelial plane: a proposed model for studying endothelium around atherosclerotic plaques
Name of the Authors :UM Balaguru, L Sundaresan, J Manivannan, R Majunathan, S Chatterjee
Scientific Reports 6 (1), 1-15 (2016)

8.Prevention of cardiac dysfunction, kidney fibrosis and lipid metabolic alterations in l-NAME hypertensive rats by sinapic acid—Role of HMG-CoA reductase
Name of the Authors : T Silambarasan, J Manivannan, B Raja, S Chatterjee
European Journal of Pharmacology 777, 113-123 (2016)
 

9.Systems biological understanding of the regulatory network and the possible therapeutic strategies for vascular calcification
Name of the Authors :J Manivannan, M Prashanth, VS Kumar, M Shairam, J Subburaj
Molecular BioSystems 12 (12), 3683-3694 (2016)

10.Oral administration of veratric acid, a constituent of vegetables and fruits, prevents cardiovascular remodelling in hypertensive rats: a functional evaluation
Name of the Authors :M Saravanakumar, B Raja, J Manivannan, T Silambarasan
British Journal of Nutrition 114 (9), 1385-1394 (2015)

11.Sinapic acid protects heart against ischemia/reperfusion injury and H9c2 cardiomyoblast cells against oxidative stress
Name of the Authors :T Silambarasan, J Manivannan, MK Priya, N Suganya, S Chatterjee, B Raja
Biochemical and Biophysical Research Communications 456 (4), 853-859 (2015) DOI: )

12.Systems pharmacology and molecular docking strategies prioritize natural molecules as cardioprotective agents
Name of the Authors :J Manivannan, T Silambarasan, R Kadarkarairaj, B Raja
RSC Advances 5 (94), 77042-77055 (2015)

13.Diosgenin, a steroidal saponin, prevents hypertension, cardiac remodeling and oxidative stress in adenine induced chronic renal failure rats
Name of the Authors :J Manivannan, J Shanthakumar, T Silambarasan, E Balamurugan, B Raja
RSC Advances 5 (25), 19337-19344 (2015)

14.Sinapic acid prevents hypertension and cardiovascular remodeling in pharmacological model of nitric oxide inhibited rats
Name of the Authors :T Silambarasan, J Manivannan, MK Priya, N Suganya, S Chatterjee, B Raja PloS one 9 (12), e115682 (2014)

15.Diosmin pretreatment improves cardiac function and suppresses oxidative stress in rat heart after ischemia/reperfusion
Name of the Authors :O Senthamizhselvan, J Manivannan, T Silambarasan, B Raja
European Journal of Pharmacology 736, 131-137 (2014)

16.Diosgenin interferes coronary vasoconstriction and inhibits osteochondrogenictransdifferentiation of aortic VSMC in CRF rats
Name of the Authors :J Manivannan, J Shanthakumar, P Arunagiri, B Raja, E Balamurugan
Biochimie 102, 183-187 (2014)
 

17.Valproic acid attenuates blood pressure, vascular remodeling and modulates ET-1 expression in L-NAME induced hypertensive rats
Name of the Authors :T Rajeshwari, B Raja, J Manivannan, T Silambarasan
Biomedicine and Preventive Nutrition 4 (2), 195-202 (2014)

18.Valproic acid prevents the deregulation of lipid metabolism and renal renin–angiotensin system in l-NAME induced nitric oxide deficient hypertensive rats
Name of the Authors :T Rajeshwari, B Raja, J Manivannan, T Silambarasan, T Dhanalakshmi Environmental Toxicology and Pharmacology 37 (3), 936-945 (2014)

19.In Silico Sequence Analysis Homology Modelling and Functional Annotation of Toxin I Hypothetical Protein of Catfish Plotosuslineatus
Name of the Authors :T. R. Barathkumar, J Manivannan, MThangaraj
International Journal of Pharmaceutical & Biological Archives; 4(4): 753 – 757(2013)

20.Effect of diosgenin on cardiac tissue lipids, trace elements, molecular changes, TNF-α and IL-6 expression in CRF rats
Name of the Authors :J Manivannan, J Shanthakumar, K Rajeshwaran, P Arunagiri, E Balamurugan
Biomedicine & Preventive Nutrition 3 (4), 389-392 (2013)

21.Diosgenin improves vascular function by increasing aortic eNOS expression, normalize dyslipidemia and ACE activity in chronic renal failure rats
Name of the Authors :J Manivannan, E Balamurugan, T Silambarasan, B Raja
Molecular and Cellular Biochemistry 384 (1), 113-120 (2013)

22.Diosgenin prevents hepatic oxidative stress, lipid peroxidation and molecular alterations in chronic renal failure rats
Name of the Authors :J Manivannan, P Arunagiri, J Sivasubramanian, E Balamurugan
International Journal of Nutrition, Pharmacology, Neurological Diseases; 3:289-93 (2013)
 

23.Determination of aluminium induced metabolic changes in mice liver: A Fourier transform infrared spectroscopy study
Name of the Authors :S Sivakumar, J Sivasubramanian, CP Khatiwada, J Manivannan, B Raja
SpectrochimicaActa Part A: Molecular and Biomolecular Spectroscopy 110, 241-248 (2013) 

24.Diosgenin attenuates vascular calcification in chronic renal failure rats
Name of the Authors :J Manivannan, TR Barathkumar, J Sivasubramanian, P Arunagiri, B Raja, E Balamurugan
Molecular and cellular biochemistry 378 (1), 9-18 (2013)

25.Computational systems biology of oxLDL induced macrophage foam cellformation-A multilayer regulatory network analysis of atherogenic process
Name of the Authors :M Prashanth, J Manivannan, T Silambarasan, E.Balamurugan
Journal of Chemical and Pharmaceutical Research; 5(10):39-44 (2013) )

26.Computational systems pharmacology and docking explored diosgenin targets causal and effectors pathogenic signalling network of vascular calcification
Name of the Authors :J Manivannan, TRB Kumar, P Arunagiri, E Balamurugan
J. Chem. Pharm. Res 5, 161-167 (2013) )

27.Aluminium induced metabolic changes in kidney and heart tissue of mice: a Fourier transform infrared spectroscopy study
Name of the Authors :S Sivakumar, J Sivasubramanian, J Manivannan, B Raja
RSC Advances 3 (43), 20896-20904 (2013)

28.Molecular metabolic fingerprinting approach to investigate the effects of borneol on metabolic alterations in the liver of nitric oxide deficient hypertensive rats
Name of the Authors :M Saravanakumar, J Manivannan, J Sivasubramanian, T Silambarasan, B Raja
Molecular and cellular biochemistry 362 (1), 203-209 (2012)

29.Evaluation of in vitro antioxidant and antimicrobial potential of methanolic leaf extract of Anisomelesmalabarica (Linn.).
Name of the Authors :B Raja, J Manivannan
Journal of Pharmacy Research 3 (7), 1471-1474 (2010)

 

2021

 

2020

 

 

Tab 3 Content
Tab 4 Content
Books Edited Year Wise
 

1.Role of antioxidants in human health
J Manivannan, T Silambarasan, J Shanthakumar, N Suganya
Omega-3 fatty acids: keys to nutritional health
Springer, Pages 501-512, 2016
ISBN 978-3-319-40458-5

2.Nutriomics-systems biology of nutrition
J. Manivannan, K. Rajeshwaran, J. Shanthakumar, P. Arunagiri, T. Tamilselvan and E. Balamurugan
Food as medicine
Nova science publishers, 441-456 (2013)
ISBN: 978-1-62417-747-7

3.Beneficial effect of fish oil
J. Shanthakumar, P. Arunagiri, K. Rajeshwaran, J. Manivannan and E. Balamurugan
Food as medicine
Nova science publishers, 37-50(2013)
ISBN: 978-1-62417-747-7

Chapter Edited Year Wise

 

 

Tab 6 Content

 

TEACHING

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

  • Environmental Toxicology
  • Data Analytics and Research Methods
  • Environmental Biotechnology
  • Environmental Health
  • Industry 4.0
  • Environmental Impact Assessment

 

PROJECTS

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

Funded Projects(National Level)

1. Science and Engineering Research Board (SERB)


Title of the project :Exploring novel pathwaysinvolved in oxidized lowdensity lipoprotein (oxLDL) induced vascular smoothmuscle cell (VSMC) foam cellformation in atherosclerosis and pharmacological effects ofmitochondria targetedantioxidant –mitoTEMPO

Funding Agency :Science and Engineering Research Board (SERB)

Amount :Rs. 19,25,000

Duration :2016-2019



1.Tamil Nadu State Council for Higher Education (TANSCHE)


Title of the project : Traffic related air pollution (TRAP) hotspots in Coimbatore city and its adverse impacts on human health – a multidisciplinary environmental health study

Funding Agency :Tamil Nadu State Council for Higher Education (TANSCHE)

Amount : Rs.Rs. 33,78,500

Duration :2021-2024

Consultancy Projects

 

RESEARCH GUIDANCE

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

 
Ongoing
S. No: 1
Student Name: M. Nagarajan
Title of Thesis: Systemic effects of BPA under hypertension – an Experimental Toxicopathological study
Status: Ongoing
Awarded
 

 

Ongoing
 
Completed
 
Ongoing
Test M.Sc. Ongoing
Completed

S. No: 11
Student Name: Maadurshni  G B
Title of Thesis: Molecular toxic effects of aluminium oxide nanoparticles (Al2O3-NPs) on vascular system
Year of Award:2021
Status: Completed

S. No: 10
Student Name: Udayakumar  I 
Title of Thesis: Spectroscopic studies on the toxic effect of Aluminium oxide nanoparticles (Al2O3)
Year of Award:2021
Status: Completed

S. No: 9 
Student Name: Tharani G K  
Title of Thesis: Toxico-pathogenic effect of aluminium oxide nanoparticles (Al2O3-NPs) on embryonic liver development
Year of Award:2021
Status: Completed 

S. No: 8
Student Name: Jeeva
Title of Thesis: Chemico-Biological Interaction Studies on Zinc Oxide Nanoparticles (ZnO-NPs) - An Environmental Health Perspective
Year of Award:2020
Status: Completed

S. No: 7
Student Name: Gayathri 
Title of Thesis: Toxico - pathological effects of zinc oxide nanoparticles (ZnO - NPs) exposure on cardiovascular system during embryonic development
Year of Award:2020
Status: Completed

S. No: 6
Student Name: S. Gorbasave
Title of Thesis: Traffic related air pollution (PM 2.5 and PM 10) in Bharathiar University Environment – A pilot study
Year of Award: 2019
Status: Completed

S. No: 5
Student Name: J. Santhiya
Title of Thesis:Effect of nickel on nucleic acid metabolism in yeast cells – a molecular toxicity study
Year of Award:2019
Status: Completed

S. No: 4
Student Name: Anupama Prakash
Title of Thesis: Effects of Nickel on lipid metabolism in yeast cells– a molecular toxicity study
Year of Award: 2019
Status: Completed

S. No: 3
Student Name: P A Sharon
Title of Thesis: Impacts of urbanization process on surface water quality in chatai chapori water way
Year of Award:2019
Status: Completed 

S. No: 2
Student Name: T. Aswathi
Title of Thesis: Effects of the molecular toxic effects on nickel on developing chick embryo muscle – an environmental health approach
Year of Award:2018
Status: Completed

S. No: 1
Student Name: Sarangi S
Title of Thesis: Effects of the molecular toxic effects on nickel on developing chick embryo heart – an environmental health approach
Year of Award:2018
Status: Completed 
 

 

INSTITUTIONAL RESPONSIBILITIES

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

ADMINISTRATIVE (BHARATHIAR UNIVERSITY)

Member: SWAYAM Mentor
Period :2019 - Till date
Nature of Responsibility:Mentor

Member: DNA Sequencing Facility
Period :Jan 2020 - Till date
Nature of Responsibility:Member

AWARDS & MEMBERSHIPS

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

Awards

Travel awards


Academic Awards

Awarding agency:Ramasamy Padayatchiyar Endownment award- Annamalai University
Purpose of award:Best performance
Year:2011

Membership

Professional Bodies


Academic Bodies


Society for Biological Chemists
Member:Life
Period:2016 onwards


International Society for Heart Research
Member:Life
Period:2016 onwards


Indian Biotechnological Society
Member:Life
Period:2016 onwards


VISITS / COLLABORATIONS / OTHERS

Dr. J. Manivannan
Assistant Professor
Research Area
  • Environmental Health and Medicine
  • Molecular Systems Biology
  • Exposomics and Toxicomics

0422-2428399

9894907931

ACADEMIC IDENTITY Scopus   ORCID   Google Scholar   Publons   Vidwan / IRINS

Visits

 

Collaborators

 

Others