The Department of Commerce was started in the year 1990 as a Research Department with Ph.D as the only course with Finance, Marketing, Accounting and Human Resource Management as specialisation. Apart from the core specialization the department is also contributing to the allied activities such as Consumer issues and Skill Development.

The department came into existence as part of the PG centre of Madras University in the year 1973. Since 1982, the department has emerged as one of the full-fledged university department of Bharathiar University. During the inception, the department functioned with 3 faculty members.

The Department of Botany was instituted in the Postgraduate Centre of the University of Madras in 1972. The Department is offering M.Sc. in Plant Science, M.Phil. and Ph.D. programmes in Botany in the fields of Mycology, Microbiology, Plant Physiology, Nutraceuticals and Phytomedicine, Tissue culture and Reproductive Biology, Genetics and Plant Breeding and Plant systematics.

The Department of Biotechnology at Bharathiar University was established in the year 1990 with 2 faculty exclusively for research under the headship of Prof. R. Boopathy, a Biochemist and Prof. K. Swaminathan, a Microbiologist. In 2001, post-graduate programmes were started, M.Sc. Industrial Biotechnology followed by M.Sc. Biotechnology in the subsequent year.

In the year 2001, Bioinformatics programme was initiated under Department of Botany. Research Degrees (Ph.D. and M.Phil.) were introduced at 2005. Then created as independent Department under School of Life Sciences 2007. DBT Bioinformatics Facility was inaugurated in the year 2008. P. G. Diploma in Cheminformatics was started as an innovative programme with the support of UGC at 2011. Totally 6 faculties are working in the department.

The Department of Biochemistry was instituted in 2015. Biochemistry is the point where chemistry, biology and medicine meets and it deals with the molecular interactions between various intra and inter cellular compartments of living organisms and diseases.

The Department of Applied Mathematics was started as a department in Bharathiar University during June 2008 under the headship of Professor Dr.S.P.Anjalidevi with four guest lecturers.

Bharathiar School of Management and Entrepreneur Development (BSMED) was established in 1984 and had been recognized by the UGC, New Delhi as a "Center for excellence" for teaching and Research in management. BSMED is located in the industrial city, Coimbatore, within the confines of Bharathiar University. The campus covers a lush landscape and tranquil surrounding which creates the ideal atmosphere for the unending pursuit of knowledge.